7 Best Hydroxytyrosol Supplements for Optimal Health in 2025

Hydroxytyrosol is a natural polyphenol celebrated for its powerful antioxidant and health-protective properties. Sourced mainly from olives (both the fruit and leaves) and extra virgin olive oil, this compound is a key contributor to the renowned benefits of the Mediterranean diet​. 

It boasts one of the highest antioxidant capacities ever recorded—with an ORAC value around 40,000 µmol TE/g, far exceeding that of green tea or CoQ10​. Such potency translates into a host of potential health benefits, from heart and vascular health to anti-inflammatory and neuroprotective effects​. 

Given hydroxytyrosol’s rising popularity, many supplements now offer concentrated doses of this olive-derived antioxidant. We’ve researched and hand-picked the seven best hydroxytyrosol supplements on the market, highlighting popular, high-quality brands. Each delivers unique features and potency—and one stands out above the rest. 

Here are our top seven picks:

• Best Overall: Olivea EVOO & Hydroxtyrosol Supplement — Innovative dual capsule with 20 mg hydroxytyrosol and extra virgin olive oil for superior absorption

• Highest Potency: ProHealth Hydroxytyrosol Extreme — Delivers 25 mg of pure hydroxytyrosol (Olea25®) per veggie cap for maximum antioxidant punch

• Best Synergistic Formula: Vinatura Olive Leaf & Fruit — Combines 80 mg hydroxytyrosol and 200 mg oleuropein plus black seed oil in one capsule for comprehensive olive polyphenol benefits

• Best Value: Swanson Superior Herbs Olea25 — Uses the same Olea25® 25% hydroxytyrosol extract in an affordable, Non-GMO veggie capsule

• Best Liquid Extract: Barlean's Olive Leaf Complex — Full-spectrum olive leaf liquid standardized to 40% oleuropein (approximately 95 mg) with naturally occurring hydroxytyrosol and other polyphenols

• Best Powder: Wonderland Herbs Hydroxytyrosol — 20% hydroxytyrosol olive extract powder for flexible dosing, custom blends, or making your own capsules

• Best Organic Whole-Food: Olivie Anti-Age — USDA Organic olive polyphenol capsules (leaf & fruit) extremely rich in hydroxytyrosol, boasting an ORAC value 200× higher than curcumin for anti-aging support
  

How We Rate Hydroxytyrosol Supplements

What separates an outstanding hydroxytyrosol supplement from a mediocre one? After evaluating dozens of products, we've discovered it comes down to several crucial elements:

Source and Quality

Nature knows best! We strongly favor supplements derived from premium olive sources over synthetic versions. Products using organic olives or "medical grade" extra virgin olive oil (like Olivea) earned our highest marks. We also checked for clean manufacturing—nobody wants unnecessary fillers in their wellness routine.

Concentration and Potency

When it comes to hydroxytyrosol, potency matters. The best supplements deliver a meaningful dose (typically 5-25+ mg) and transparently state their standardization. Think of it this way: higher mg equals more antioxidant protection. All our selections exceed the 5 mg threshold research links to heart health benefits.

Bioavailability and Formulation 

Can your body actually use it? Hydroxytyrosol loves fat—it's how your body best absorbs it. We were particularly impressed by innovative formulations that enhance absorption, like Olivea's clever capsule-in-capsule design that suspends hydroxytyrosol in olive oil.

Third-Party Testing and Purity

Trust but verify! We favored brands that invest in third-party testing and appropriate certifications. Products free from contaminants and accurately standardized rose to the top of our list.

Form and Convenience

Whether you prefer swallowing a capsule, adding drops to your smoothie, or mixing powder into your morning routine, we've included excellent options for every preference.

Hydroxytyrosol Supplements Ranked (Comparison Table)

What separates good from great in the hydroxytyrosol world? Our side-by-side comparison reveals the distinctive strengths of each top contender. 

Spoiler alert: Olivea claims the crown with its perfect trifecta of potent dosage, breakthrough delivery system, and uncompromising quality standards. 

The table below cuts through the marketing noise to show exactly what you're getting—from form factor to hydroxytyrosol content to standout features that make each product shine.

 

Note: “HT” = hydroxytyrosol. Some values are approximate or based on standardization; actual absorbable amounts may vary. 

1. Olivea EVOO & Hydroxytyrosol Supplement – Best Overall

Form: Capsule-in-capsule (double capsule design)

Hydroxytyrosol Content: 20 mg per capsule

Notable Features: Medical-grade extra virgin olive oil; Capsule-in-capsule delivery; Inner capsule of pure hydroxytyrosol, outer capsule of extra virgin olive oil; Made from Greek olives; Physician-developed formula; Third-party tested; All natural, non-GMO, vegan; Preservative-free, dairy-free, gluten-free.

About Olivea

Olivea is a breakthrough supplement that merges the wisdom of the Mediterranean diet with modern delivery technology. Developed in collaboration with cardiologists, it’s the world’s first “medical grade” extra virgin olive oil (EVOO) and hydroxytyrosol supplement. 

Each Olivea capsule actually contains two capsules in one: a smaller inner capsule holding 20 mg of hydroxytyrosol, suspended inside a larger outer capsule filled with high-phenolic extra virgin olive oil. This “cap-in-cap” design is made in Greece from premium Kalamata olives and is third-party tested for purity. 

Olivea’s all-natural formula is Non-GMO, vegan, and free of preservatives, dairy, and gluten, making it as clean as it is innovative.

Why We Chose Olivea

Olivea earned our top spot because it checks every box: potency, bioavailability, and quality. The 20 mg of hydroxytyrosol per serving is a hefty dose—over four times the minimum amount shown to protect LDL cholesterol per EFSA guidelines. 

Thanks to the EVOO in the outer capsule, this hydroxytyrosol is delivered in its natural lipid environment, which ensures superior absorption and bioavailability. In essence, Olivea replicates the way you’d get hydroxytyrosol by consuming olive oil, but in a far more concentrated form. In fact, just one Olivea capsule contains as much pure hydroxytyrosol as about 100 tablespoons of a typical extra virgin olive oil—all in a tiny 4-calorie capsule! 

Olivea’s remarkable efficacy is backed by science: its formula was designed based on rigorous studies linking olive polyphenols to heart health, vascular function, and longevity. Olivea delivers tangible benefits like helping maintain healthy blood pressure and cholesterol levels, improving blood vessel elasticity, and fighting inflammation (key for heart and brain health). If you’re seeking the closest thing to tapping the “Mediterranean miracle” in a pill, Olivea is it.

Pros & Cons of Olivea

Who Is Olivea For?

Olivea is ideal for health enthusiasts and preventative wellness seekers who want the absolute best hydroxytyrosol supplement. If you’re serious about cardiovascular health, longevity, or anti-aging, Olivea provides a clinical-grade dose of antioxidants in a convenient daily capsule. 

Olivea is especially suited for those who value science-backed formulas—perhaps you’ve read about the Mediterranean diet’s heart benefits and want to capture that in a supplement. Olivea’s easy one-capsule daily regimen is great for busy individuals who won’t stick to consuming large amounts of olive oil or olive extracts each day. 

Additionally, because it’s free of common allergens and is 100% plant-based, it’s a wonderful choice for people with dietary restrictions (vegans, gluten-free, etc.). If you demand purity, potency, and proven effectiveness, Olivea was made for you.

2. ProHealth Hydroxytyrosol Extreme – Highest Potency Capsule

Form: Vegetarian capsule

Hydroxytyrosol Content: 25 mg per capsule (from 100 mg Olea25® olive leaf extract)

Notable Features: Uses Olea25®—a patented extract standardized to 25% hydroxytyrosol; Extremely high ORAC antioxidant value; Third-party tested, no fillers.

About ProHealth Hydroxytyrosol Extreme

ProHealth's Hydroxytyrosol Extreme™ delivers 100 mg of Olea25® per capsule, yielding 25 mg of pure hydroxytyrosol. Olea25® is a trademarked olive leaf extract with an unprecedented 25% concentration (compared to typical 5-10% extracts). 

Made in the USA under strict quality controls, this supplement is free from common allergens with vegetarian capsules containing only rice flour as a flow agent. The formula is backed by research on hydroxytyrosol's anti-inflammatory, heart-protective, and anti-aging effects. Each bottle provides 90 capsules, offering a 3-month supply of potent antioxidant support.

Why We Chose ProHealth Hydroxytyrosol Extreme

ProHealth's Hydroxytyrosol Extreme stands out for its exceptional potency—25 mg per capsule surpasses levels in many clinical studies. The product utilizes Olea25®, considered the world's strongest olive polyphenol extract, with an impressive ORAC score of 68,576 μmol TE (15 times higher than green tea and 3 times higher than CoQ10). This translates to powerful free-radical scavenging throughout the body, making it ideal for anti-aging, immune support, and inflammation reduction. 

ProHealth's credibility since 1988 and focus on evidence-based supplements adds reliability. This no-frills product offers pharmacological-level hydroxytyrosol for those seeking advanced antioxidant protection, particularly biohackers, longevity enthusiasts, or individuals with specific health goals like blood pressure support, cholesterol balance, and joint health. Its simple formulation allows easy integration with other supplements without interaction concerns.

Pros & Cons of ProHealth Hydroxytyrosol Extreme

Who Is ProHealth Hydroxytyrosol Extreme For?

ProHealth Hydroxytyrosol Extreme is ideal for health-savvy individuals seeking maximum antioxidant support, particularly those tracking ORAC values, biohacking their diet, or following anti-aging regimens. 

It's well-suited for people with specific cardiovascular or metabolic health goals, especially those with family history of heart issues wanting to support healthy cholesterol and blood pressure. 

Athletes may benefit from its ability to combat exercise-induced oxidative stress. Those seeking general wellness might find a lower-dose or whole-food option sufficient. 

This product is essentially for the "advanced user" who understands hydroxytyrosol's benefits and desires its most concentrated form.

3. Vinatura Olive Leaf & Fruit – Best Synergistic Formula

Form: Vegetarian capsule

Hydroxytyrosol Content: ~80 mg per capsule (from 200 mg olive fruit extract at 40% HT)

Notable Features: Combines olive fruit extract (40% hydroxytyrosol) with olive leaf extract (50% oleuropein) in one capsule; Plus 50 mg black seed oil extract for added antioxidant and anti-inflammatory support; High-strength multi-polyphenol formula.

About Vinatura Olive Leaf & Fruit

Vinatura's Olive Leaf & Fruit supplement takes a comprehensive approach by blending two potent olive extracts: fruit extract standardized to 40% hydroxytyrosol and leaf extract standardized to 50% oleuropein. 

Each capsule delivers approximately 80 mg of hydroxytyrosol and 200 mg of oleuropein, mirroring the natural combination found in whole olives. The formula is enhanced with 50 mg of Nigella sativa (black seed) extract, which provides additional anti-inflammatory compounds that synergize with olive polyphenols. 

The ingredients are sustainably sourced from Spanish olives and packaged in easy-to-swallow vegetarian capsules without artificial additives. Vinatura offers a 90-day refund guarantee, with each bottle typically containing a one-month supply (60 capsules).

Why We Chose Vinatura Olive Leaf & Fruit

Vinatura's formula stands out by capturing the entourage effect of olive polyphenols, combining hydroxytyrosol with oleuropein rather than isolating a single compound. This pairing supports multiple health aspects simultaneously—hydroxytyrosol tackles free radicals while oleuropein benefits immune function and metabolism. Together, they address cardiovascular health comprehensively from different angles.

The exceptional potency (80 mg hydroxytyrosol with 200 mg oleuropein) delivers substantial benefits in a single daily capsule. The addition of black seed extract enhances effectiveness against inflammation and oxidative stress while potentially improving absorption of the olive compounds.

Pros & Cons of Vinatura Olive Leaf & Fruit

Who Is Vinatura Olive Leaf & Fruit For?

Vinatura Olive Leaf & Fruit is ideal for holistic health seekers who prefer a multifaceted approach. It's particularly well-suited for individuals concerned about both cardiovascular and immune health, and those who understand the complementary benefits of oleuropein and hydroxytyrosol. 

Middle-aged to older adults targeting olive's anti-aging benefits, people with inflammatory issues, or those wanting to capture Mediterranean diet benefits in supplement form will appreciate this formula. Athletes can also benefit from its broad antioxidant network for recovery. 

Best for those committed to a daily regimen with a higher supplement budget who want a complete "total olive" solution in one convenient capsule.

4. Swanson Superior Herbs Olea25 – Best Value

Form: Vegetarian capsule

Hydroxytyrosol Content: 25 mg per capsule (from Olea25® olive leaf extract, 100 mg)

Notable Features: Utilizes the same Olea25® 25% hydroxytyrosol extract as premium brands; Trusted large supplement brand (Swanson); Non-GMO, vegetarian formula; Economical price per capsule.

About Swanson Superior Herbs Olea25

Swanson's Superior Herbs Olive Leaf Extract delivers high-dose hydroxytyrosol at an affordable price. Each capsule contains 100 mg of Olea25® extract standardized to 25% hydroxytyrosol, yielding 25 mg of pure hydroxytyrosol—identical in strength to more expensive brands. 

Part of Swanson's higher potency herbal line, this product comes in vegetarian capsules free of unnecessary additives. Swanson adheres to GMP quality standards and performs purity testing, making this a reliable yet economical choice. 

A typical bottle contains 60 capsules (two-month supply), with minimal additional ingredients beyond the Olea25® extract, vegetable capsule, and rice flour. The product is non-GMO and vegetarian-friendly.

Why We Chose Swanson Superior Herbs Olea25

We selected Swanson's Olea25 as the best value option because it democratizes a top-tier ingredient at a reasonable price. Using the exact same patented Olea25® extract found in premium formulations, this product delivers the high ORAC, highly purified 25 mg dose of hydroxytyrosol known for cardiovascular and longevity benefits—without the premium price tag. 

Swanson's reliability is another key factor; operating since 1969 with millions of customers, they offer consistency and trustworthiness backed by in-house quality control. This Superior Herbs product features a 25% hydroxytyrosol extract, which is exceptional for its price point. For those planning long-term hydroxytyrosol supplementation, Swanson makes it financially sustainable.

While this formula doesn't include extras like olive oil or other polyphenols, its straightforward approach offers the perfect intersection of potency, purity, and affordability for those seeking quality hydroxytyrosol without breaking the bank.

Pros & Cons of Swanson Olea25

Who Is Swanson Superior Herbs Olea25 For?

Swanson's Olea25 is perfect for budget-conscious consumers seeking high-quality hydroxytyrosol. It's ideal for those who understand hydroxytyrosol's benefits but don't want to pay premium prices. This supplement suits people who already trust Swanson products or prefer major brands with established reputations.

The straightforward formulation makes it compatible with other supplements in your regimen. New hydroxytyrosol users will find this an accessible way to experience its antioxidant and heart health benefits before committing to pricier options. 

It's particularly suitable for students, retirees on fixed incomes, or families looking for an affordable yet effective daily supplement.

5. Barlean’s Olive Leaf Complex – Best Liquid Extract

Form: Liquid tincture (olive leaf extract in water/glycerin base)

Hydroxytyrosol Content: Approximately 0.75–1 mg per 15 mL serving (naturally present, not isolated)

Notable Features: Full-spectrum fresh olive leaf extract standardized to 40% oleuropein (providing approximately 95 mg oleuropein per tablespoon); Contains naturally occurring hydroxytyrosol, verbascoside, tyrosol and other polyphenols; Available in unflavored or peppermint flavor; Can be taken straight or mixed into beverages.

About Barlean's Olive Leaf Complex

Barlean's Olive Leaf Complex is a liquid supplement capturing the broad benefits of olive leaves in an absorbable form. This family-owned company sources fresh-picked olive leaves from Spain and processes them into a liquid extract that preserves their nutrients. 

Each tablespoon (15 mL) contains 40% oleuropein (about 95 mg) along with naturally occurring hydroxytyrosol, tyrosol, verbascoside, luteolin, and other polyphenols—essentially mimicking what you'd get from raw olive leaf in concentrated form. 

The alcohol-free formula uses a water and vegetable glycerin base, offering an earthy olive taste in the original version or a refreshing peppermint option. The product is free from sugar, gluten, and artificial ingredients, and comes in various bottle sizes, with a softgel version also available.

Why We Chose Barlean's Olive Leaf Complex

We selected Barlean's as the top liquid hydroxytyrosol supplement because of the unique advantages liquids offer: faster absorption (compounds are already dissolved) and flexible dosing. While the hydroxytyrosol content (approximately 1 mg per serving) is significantly lower than concentrated capsules, Barlean's provides a full spectrum of polyphenols working together—like a "juice" of olive leaf in a more natural state.

This liquid format is convenient for those who dislike pills, as it can be taken directly or mixed into beverages. The peppermint flavor makes it one of the more enjoyable herbal extracts to consume. Barlean's is also widely accessible in health food stores and online retailers.

Pros & Cons of Barlean’s Olive Leaf Complex

Who Is Barlean’s Olive Leaf Complex For?

Barlean's Olive Leaf Complex is perfect for those preferring natural, food-like supplements with flexible dosing. It's ideal for smoothie and health tonic enthusiasts, families (alcohol-free with kid-friendly dosing options), and those focused on immune support. 

This liquid option suits people with busy routines who can take a quick spoonful in the morning, those with swallowing difficulties, or anyone seeking a gentle introduction to olive supplements. The plant-based formula (unlike gelatin softgels) appeals to those with dietary restrictions. 

In essence, it's for anyone valuing ease of use and a broad, natural polyphenol profile over high-dose specificity.

6. Wonderland Herbs Hydroxytyrosol Powder – Best Powder

Form: Bulk powder (olive extract standardized to 20% hydroxytyrosol)

Hydroxytyrosol Content: 20% by weight (e.g. approximately 200 mg hydroxytyrosol per 1 gram of powder)

Notable Features: Pure powdered extract with no fillers; Allows customized dosing; Ideal for mixing into smoothies, protein shakes, or making DIY capsules; Long shelf life when stored properly.

About Wonderland Herbs Hydroxytyrosol Powder

Wonderland Herbs offers a high-purity olive extract powder standardized to 20% hydroxytyrosol, delivering approximately 200 mg of hydroxytyrosol per gram. This light tan to off-white powder comes in vacuum-sealed packaging to preserve freshness. With no added ingredients or excipients, it's simply pure olive extract powder with a relatively neutral taste (though some bitterness is present). 

Users typically measure their desired dose using a milligram scale or micro-scoop, with 250 mg of powder providing about 50 mg of hydroxytyrosol. This bulk format significantly reduces cost per serving compared to pre-made capsules while allowing complete dosage customization.

Why We Chose Wonderland Herbs Hydroxytyrosol Powder

We selected Wonderland Herbs' powder for its exceptional versatility and value, particularly for those needing higher doses. The 20% concentration exceeds many competing olive powders, allowing smaller amounts to achieve effective dosages. Its additive-free purity appeals to those avoiding unnecessary ingredients, while its versatility enables multiple consumption methods— from mixing into beverages to DIY encapsulation. 

The powder form dramatically reduces cost per milligram, making it ideal for long-term users. While requiring more effort to measure, this format provides complete control over dosage and delivery, making it the optimal choice for serious supplement users wanting maximum flexibility and potency without any fillers or additional ingredients.

Pros & Cons of Wonderland Herbs Hydroxytyrosol Powder

Who Is Wonderland Herbs Hydroxytyrosol Powder For?

Wonderland Herbs Hydroxytyrosol Powder is ideal for experienced supplement users, DIYers, and practitioners who value flexibility in dosing. It suits those who already prepare protein shakes or use bulk supplements like collagen or vitamin C. 

The product is perfect for individuals following specific protocols requiring precise dosages, healthcare professionals creating custom regimens, or daily smoothie enthusiasts wanting to add potent antioxidants. It's also beneficial for those with pill fatigue or swallowing difficulties.

This product isn't recommended for casual users or supplement beginners who might find measuring doses inconvenient or dislike the bitter taste. 

7. Olivie Anti-Age – Best Organic Whole-Food Option

Form: Vegetarian capsules (500 mg per capsule)

Hydroxytyrosol Content: Not individually standardized (whole olive polyphenol complex)—extremely high polyphenol content equivalent to ~5,500× the polyphenols of regular EVOO (including hydroxytyrosol, oleuropein, tyrosol, etc.)

Notable Features: 100% USDA Organic; Capsules contain powdered organic olive leaves, young olive shoots, and olive fruits plus organic olive oil; Exceptionally high ORAC antioxidant value (200× higher than even curcumin); Clinically validated by EFSA for antioxidant effects.

About Olivie Anti-Age

Olivie Anti-Age takes a whole-plant approach to delivering olive polyphenols. Using a proprietary process, olive trees are cultivated under harsh desert conditions in Morocco, resulting in olives and leaves extraordinarily rich in polyphenols. These organic olive fruits, leaves, and young buds are harvested, milled into powder, and encapsulated with a bit of organic olive oil to enhance bioavailability. Each 500 mg vegetable capsule contains "food in a capsule," capturing the synergy of all olive antioxidants and nutrients.

The product boasts remarkable potency—analysis shows polyphenol content 5,500 times greater than regular extra virgin olive oil, with an ORAC value over 250,000 μmol TE per 100g. The product is USDA Organic, halal, and kosher, with no synthetic additives. Each box contains 40 capsules, with a recommended dosage of 1–2 capsules daily.

Why We Chose Olivie Anti-Age

Olivie Anti-Age represents the philosophy that sometimes the whole is greater than the sum of its parts. While other products offer isolated hydroxytyrosol, Olivie delivers it in its native context with all co-factors from the olive plant.

Though Olivie makes bold marketing claims, they're supported by ORAC testing and EFSA validations. This single-ingredient product (olive) naturally contains multiple polyphenols, fiber, and micronutrients in a format that's essentially an olive superfood concentrate.

The "Anti-Age" name reflects its unparalleled spectrum of antioxidants that combat oxidative stress and inflammation—key drivers of aging. The inclusion of organic olive oil in the capsules smartly addresses bioavailability while maintaining a 100% olive-derived product.

Pros & Cons of Olivie Anti-Age

Who Is Olivie Anti-Age For?

Olivie Anti-Age is perfect for natural wellness devotees who prefer food-based nutrients over isolated compounds. It appeals to those seeking anti-aging benefits from whole-food sources, individuals with sensitive systems, and people committed to organic lifestyles. 

This supplement suits those who already consume olive products for health but want concentrated benefits without extra calories. It's excellent for skin health enthusiasts and appeals to consumers willing to pay more for an artisanal product that delivers olive power in its most natural form to support overall health and youthful vitality.

The Best Hydroxytyrosol Supplement: Final Recommendations

Choosing the right hydroxytyrosol supplement depends on your health goals and personal preferences, but across all our research Olivea stands out as the best overall choice. It earned this top spot by delivering a clinical-grade dose of hydroxytyrosol (20 mg) in a format that maximizes absorption—the innovative capsule-in-capsule design with extra virgin olive oil truly sets it apart.

Olivea exemplifies what a premium supplement should be: high potency, bioavailable, and backed by science. If you want a singular recommendation, Olivea is the one that shines in every category, from purity and formulation to convenience.

That said, every supplement on our list is a quality pick tailored to different needs.For maximum potency, ProHealth's Hydroxytyrosol Extreme delivers 25 mg per pill. Those preferring a whole-olive approach will appreciate Vinatura's synergistic blend of hydroxytyrosol, oleuropein, and black seed. Budget-conscious consumers can choose Swanson's Olea25 for the same patented extract as premium brands at a lower price.

If pills aren't your preference, Barlean's Olive Leaf Liquid offers a gentle, full-profile extract in tasty liquid form. DIY enthusiasts can use Wonderland Herbs' powder to customize dosages or create personalized antioxidant blends. For organic purists and anti-aging aficionados, Olivie Anti-Age provides a holistic olive polyphenol experience that closely mimics the Mediterranean diet's benefits in supplement form.

In wrapping up, our top recommendation remains Olivea for its all-around excellence—it’s the supplement that most effectively captures hydroxytyrosol’s benefits in a convenient daily form. Try Olivea EVOO & Hydroxytyrosol Supplement today—you’ll be investing in your heart, brain, and longevity with each capsule.